Alzheimer's disease can be overwhelming for both the patient and the patient’s loved ones. In the early stages of Alzheimer's disease, patients and their loved ones may become frustrated with memory loss or the inability to complete simple tasks. This may result in depression or anger. As the disease progresses, patients usually experience more substantial dementia that may affect their ability to perform self-care tasks such as bathing and dressing and may require professional care in a nursing home.

Alzheimer's disease also presents certain safety issues. For example, people with Alzheimer's disease are more likely to be injured around the home. Injuries may be caused by falls that occur when the parts of the brain responsible for balance and coordination are affected. Additionally, the memory loss that is associated with Alzheimer's disease may make it unsafe for patients to cook (especially over a direct heat source), drive and otherwise live independently. It may be necessary to take certain safety precautions in the home, such as installing railings around the bath or shower and setting the water temperature to a lower level to avoid scalding.

Family support is an essential aspect of Alzheimer's care and treatment. It is important that loved ones understand the patient’s limitations and adjust their behavior and communication strategies accordingly. As the disease progresses, patients may exhibit strange behavior such as aggression or forgetting the names of immediate relatives. This can be a traumatic experience for close friends and family. In some cases, individual or group therapy is beneficial for those coping with the consequences of Alzheimer's disease in a close friend or family member.