Amenorrhea may be accompanied by various other symptoms depending on its underlying cause. Accompanying symptoms may help physicians to diagnose conditions causing the absence of menstruation. Related symptoms may include:

• Extreme loss of weight due to an eating disorder (e.g., anorexia nervosa, bulimia) or serious illness (e.g., cancer)
  
  
• Acne, excess body hair (hirsutism) or excessive weight gain, among other symptoms associated with polycystic ovarian syndrome (PCOS)
  
  
• Secretions of the breast not related to pregnancy or nursing (galactorrhea) due to high levels of the hormone prolactin in the blood (hyperprolactinemia)
  
  
• Arthritis, loss of sexual desire and shortness of breath (dyspnea) caused by excessive amounts of iron in the body resulting from hemochromatosis
  
  
• Underactive thyroid gland (hypothyroidism)
  
  
• Low blood pressure, lack of breast milk production and loss of pubic hair caused by a rare condition involving the pituitary gland can occur in women after severe blood loss during childbirth (Sheehan syndrome)
  
  
• Weight gain around the midsection and upper back, exaggerated facial roundness, high blood pressure and muscle weakness occurring when the body produces and/or is exposed to high levels of the hormone cortisol for a prolonged period of time (Cushing syndrome)