In many cases, amnesia clears on its own and requires no treatment. However, if an underlying physical or mental disorder is detected, it should be treated if possible.  Psychotherapy is also sometimes used to help patients recover from amnesia. In particular, hypnosis may help patients recall memories they have forgotten.

Family support can be a crucial element in helping a patient to recover from amnesia. An approach called reality orientation aids in easing patients back into their environment by surrounding them with familiar music, objects and photographs. 

Some forms of amnesia result in permanent memory loss that cannot be treated. However, even in such cases, patients may be helped with the use of memory aids and a structured environment.

In addition, researchers are currently studying the effectiveness of medication in improving memory loss in patients who sustained traumatic brain injuries.