Angiotensin-II receptor blockers (ARBs) are only one part of a treatment plan for high blood pressure, heart failure or other conditions. That plan usually includes a number of lifestyle changes including weight loss, eating a heart-healthy diet, regular exercise and more. ARBs reduce the symptoms, but do not cure the underlying condition. Therefore, many patients taking ARBs will be on the medication for the rest of their lives, provided no serious side effects occur. 

Often, the symptoms that led the patients to seek medical attention will stop once ARBs are introduced. Patients should still continue to take their medication exactly as directed and to keep all scheduled follow-up appointments with their physician.

When first taking ARBs, patients may be advised to avoid driving or operating heavy machinery until they know how the medication will affect them. Patients are more likely to have side effects from ARBs or other antihypertensives if they spend too much time in the heat. Therefore, patients should be certain to drink enough liquids during exercise or in hot weather. Patients may also be directed to take their own blood pressure readings regularly, reporting anything unusual to their physicians.

Patients taking ARBs should inform their physician if they become ill from any cause, especially if severe diarrhea or vomiting occurs. These conditions can cause the body to lose too much water and potassium, leading to low blood pressure (hypotension).

Patients should not stop taking ARBs abruptly unless advised by their physician. Doing so might lead to medical complications.

Pregnant patients should not take ARBs, and women who are or are planning to become pregnant should tell their physicians before taking ARBs.