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Women should not take benzodiazepines during pregnancy or while breastfeeding. Women who take benzodiazepines during pregnancy increase the risk of having a newborn who exhibits signs of withdrawal from the drug. In addition, benzodiazepines may cause neonatal flaccidity. Breastfeeding while taking benzodiazepines may increase the risk of infant sedation, feeding difficulties and weight loss.

Although the effects of buspirone on pregnancy and breastfeeding are not well known, women are generally advised to avoid the drug during these periods.

Antihistamines, clonidine and tigabine either should not be used or should be used only with great caution by women who are pregnant or breastfeeding.

All women should consult their physician before taking any medication during pregnancy or while breastfeeding.