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Anti Inflammatory Drugs

Also called: Anti Inflammatories

- Summary
- About anti-inflammatory drugs
- Types and differences
- Conditions treated
- Conditions of concern
- Potential side effects
- Drug or other interactions
- Symptoms of overdose
- Pregnancy use issues
- Child use issues
- Elderly use issues
- Questions for your doctor

Reviewed By:
David Slotnick, M.D.

Types and differences of anti-inflammatories

Anti-inflammatory drugs are either nonsteroidal or steroidal. Nonsteroidal anti-inflammatory drugs (NSAIDs) include commonly used over-the-counter painkillers and fever reducers that fall into the following categories:

  • Salicylates. Includes aspirin, which is used to relieve pain and reduce inflammation and irritation.

  • Traditional NSAIDs. The largest group in the class, available in over-the-counter and prescription form. Traditional NSAIDs include ibuprofen and naproxen.

  • COX-2 inhibitors. Help reduce pain and inflammation like traditional NSAIDs but are designed to be gentler on the stomach. However, the U.S. Food and Drug Administration (FDA) has warned that non-aspirin NSAIDs, particularly COX-2 inhibitors, may cause an increased risk of cardiovascular events. The only COX-2 inhibitor still available in the United States is celecoxib.

The FDA has approved about two dozen types of NSAIDs. Each type affects the body in a slightly different way, and individuals may respond better to one form of NSAID than another. Physicians will often switch a patient between several types of NSAIDs to find the drug that works best with the fewest side effects.

Types of NSAIDs approved for sale in the United States include:

Generic Name

Brand Name(s)

aspirin

Adprin, Alka-Seltzer, Ascriptin, Aspergum, Bayer, Bufferin, Darvon, Easprin, Ecotrin, Excedrin, Gelpirin, Genacote, Goody’s, Halfprin, Magnaprin, Norwich, PC-CAP, Percodan, Roxiprin, St. Joseph, Supac, Sureprin, Talwin, Vanquish, ZORprin

celecoxib

Celebrex

choline salicylate Arthropan
choline magnesium salicylate Trilisate

diclofenac

Cataflam, Solaraze, Voltaren

diflunisal

Dolobid

etodolac

Lodine, Lodine XL

fenoprofen

Nalfon, Nalfon 200

flurbiprofen

Ansaid

ibuprofen

Advil, Bayer Select Ibuprofen, Cramp End, Dolgesic, Excedrin IB, Genpril, Haltran, Ibifon, Ibren, IBU, Ibuprin, Ibuprohm, Ibu-Tab, Medipren, Menadol, Midol IB, Motrin, Nuprin, Pamprin-IB, Q-Profen, Rufen, Trendar

indomethacin

Indocin, Indocin SR

ketorolac

Toradol

ketoprofen

Actron, Orudis, Orudis KT, Oruvail

magnesium salicylate

Doan’s, Keygesic, Mobidin, Momentum, Novasal

meclofenamate

Meclomen

mefenamic acid

Ponstel

meloxicam

Mobic

nabumetone

Relafen

naproxen

Aleve, Anaprox, Anaprox DS,
NapraPAC, Naprelan, Naprosyn

oxaprozin

Daypro

phenylbutazone

Cotylbutazone

piroxicam

Feldene

salsalate

Argesic, Disalcid, Mono-Gesic, Salflex, Salsitab

sulindac

Clinoril

tolmetin

Tolectin


Steroidal drugs are known as corticosteroids. They include:

Generic Name

Brand Name(s)

alclometasone Aclovate
betamethasone

Alphatrex, Betatrex, Beta-Val, Diprolene, Luxiq, Maxivate

budesonide Rhinocort
clocortolone Cloderm
desonide DesOwen
dexamethasone

Aeroseb-Dex, Decaderm, Decadron, Decaspray

hydrocortisone (injection or oral)

A-hydroCort, Cortet, Hydrocortone, Solu-Cortet

hydrocortisone (topical) Ala-Cort, Ala-Scalpt, Anucort, Anu-Med, Anusert, Anusol, Aquanil, Caldecort, Cetacort, Cortagel, Cortaid, Corticaine, Cortenema, Cortifoam, Cortril, Cortizone, Dermacort, Dermarest, DermiCort, Dermtex, Gynecort, Hemorrhoidal-HC, Hemril, HydroSKIN, Hytone, LactiCare-HC, Lanicort, Locoid, Massengill, Nuprcainal, Nutracort, Orabase, Pandel, Penecort, Preparation H, Proctocort, ProctoCream, Sarnal, Scalp-Aid, Scalpcort, Texacort, Westcort, others
methylprednisolone Medrol, Meproline
prednisone

Deltasone, Liquid Pred, Meticorten, Orasone, Prednicen-M, Sterapred

prednisolone Orapred, Pediapred, Prelone
triamcinolone Aristocort, Flutex, Kenalog, Triacet

 

There are also many combination products that mix an anti-inflammatory with other ingredients, such as:

  • An NSAID with an anti-anxiety agent, an anticoagulant, a barbiturate, caffeine, a decongestant, an opioid or a sleep aid

  • A corticosteroid with an antibiotic or antifungal

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Review Date: 02-23-2007
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