The U.S. Food and Drug Administration has classified most antiparasitic agents as belonging in either category B (which means that either animal studies have shown no risk to an animal fetus, or human studies have shown no risk to a human fetus) or category C (which means animal studies have shown a risk to animal fetuses, but has not been adequately studied in humans).

Some antiparasitic agents are passed into human breast milk, though it is unknown whether others appear in breast milk. Patients should discuss the potential risks and benefits of using antiparasitic agents during pregnancy and breastfeeding with their physicians. In many cases, physicians will recommend use of precipitated sulfur as a safe and effective treatment for scabies in pregnant women.