Taking antiplatelets in the last two weeks of pregnancy may cause bleeding problems in the baby both before and after delivery. When taken in the last three months of pregnancy, antiplatelets may prolong the length of the pregnancy and the delivery. Studies on antiplatelet use earlier in pregnancy have been inconclusive. Patients who are pregnant or are trying to become pregnant should inform their physician before taking antiplatelets. In general, aspirin should be avoided during pregnancy.

Antiplatelets can pass through breast milk to the infant. However, their effect on nursing infants is unknown. Parents should weigh the benefits and risks in consultation with their physician.