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Aspirin

- Summary
- About aspirin
- Types and differences
- Conditions treated
- Conditions of concern
- Potential side effects
- Drug or other interactions
- Symptoms of overdose
- Pregnancy use issues
- Child use issues
- Elderly use issues
- Ongoing research
- Questions for your doctor

Reviewed By:
David Slotnick, M.D.

 Drug or other interactions with aspirin

Patients should consult their physician before taking any additional prescriptions, over–the–counter medications, nutritional supplements or herbal medications. Patients should not drink alcohol while taking aspirin. Certain medications can interact with aspirin, including:

  • Anticoagulants

  • Corticosteroids

  • Diabetes medications

  • Blood pressure medications, such as beta blockers and ACE inhibitors

  • Gout medications

  • Acetazolamide (medication often used to treat glaucoma)

  • Methotrexate (a disease-modifying antirheumatic drug)

  • Nizatidine (medication used to treat and prevent ulcers, as well as occasional heartburn and acid indigestion)

  • Valproic acid (an anticonvulsant used to control certain types of seizures, prevent  migraines and treat manic episodes of bipolar disorder)
There is evidence that caffeine helps boost the effects of aspirin, possibly by lifting a patient’s mood. Some brands combine aspirin and caffeine, and some experts suggest that patients can receive this benefit by taking two aspirin and drinking a cup of coffee. However, there is no proof that caffeine helps relieve pain.

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Review Date: 02-09-2007
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