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Bile Acid Resins

Also called: Bile Acid Sequestring Resins, Bile Acid Sequestrants, BAR

- Summary
- About bile acid resins
- Potential side effects
- Drug or other interactions
- Conditions of concern
- Lifestyle considerations
- Pregnancy use issues
- Child use issues
- Elderly use issues
- Questions for your doctor

Reviewed By:
Abdou Elhendy, MD, PhD, FACC, FAHA
Sumit Verma, M.D., FACC
Kerry Prewitt, M.D., FACC

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Pregnancy use issues with bile acid resins

The use of bile acid resins in pregnant women has not been studied. In animal studies, these substances have not been found to cause birth defects. Since bile acid resins are not absorbed by the body, they are unlikely to cause problems with pregnant or breast-feeding mothers or their children. These medications may inhibit the absorption of certain nutrients (vitamins A, D, K and folate) that a pregnant mother, fetus or nursing infant need – even when vitamin supplements are taken. Patients are encouraged to discuss the use of bile acid resins with their physicians, including their obstetrician-gynecologist.

Child use issues with bile acid resins

Certain bile acid resins (cholestyramine) have been tested for use in children. In appropriate doses, there is no reason to believe these medications result in different side effects, risks or benefits for children than they do for adults. However, these medications are not recommended for children under age two because cholesterol is needed for normal development. Parents are encouraged to discuss any concerns with their child’s physician.

Elderly use issues with bile acid resins

Older adults (age 60 or older) may be more sensitive to certain bile acid resins (cholestyramine, colestipol) and therefore are at greater risk of side effects. Patients are encouraged to discuss their concerns with their physicians.

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Review Date: 06-06-2007

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