• Pulmonary embolism. This is a condition in which a blood clot has become lodged in a blood vessel of the lung, blocking blood flow to the lung and causing shortness of breath.

  • Emphysema and chronic bronchitis

  • Anemia

  • Thyroid disease

  • Some types of cancer, such as lung cancer and esophageal cancer 

  • Asthma (may be accompanied with moderate to severe wheezing)

  • Some medications (e.g., nonsteroidal anti-inflammatories [NSAIDs], aspirin and beta blockers, particularly in persons with asthma)

  • Pneumonia

  • Obesity (a body mass index greater than 30)

  • Allergies, or an allergic reaction

  • Sleep apnea