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Cancer Risk & Diabetes

- Summary
- About diabetes and cancer
- Cancers related to diabetes
- Prevention methods
- Questions for your doctor

Reviewed By:
Nikheel Kolatkar, M.D.

Summary

Diabetes mellitus is a disorder in the body's ability to break down blood sugar (glucose).Cancer is a broad term used to describe more than 200 diseases characterized by abnormal cell division and the destruction of healthy body tissues. Individuals with diabetes are more likely than nondiabetics to develop certain types of cancer, according to authorities such as the National Institutes of Health.

Studies linking cancer and diabetes are often tentative and sometimes controversial. However, research most strongly associates diabetes to increased risk for developing cancers of the:

  • Colon and rectum
  • Pancreas
  • Liver
  • Endometrium (lining of the uterus)

For example, people with diabetes are up to 40 percent more likely to develop colorectal cancer, according to the American Cancer Society. There is also a possible association between diabetes and cancers of the mouth, esophagus, stomach, kidneys, bile duct, skin, breasts, cervix, ovaries, prostate and other organs.

Though the relationship between diabetes and cancer remains unclear, experts believe that hyperinsulinemia (elevated insulin levels) and obesity in people with diabetes and prediabetes are risk factors. In addition, some cancers (carcinoid tumors) and cancer treatments can cause secondary diabetes or hinder control of glucose (blood sugar).

The lifestyle factors commonly recommended for prevention and control of diabetes, such as quitting smoking, controlling weight, getting regular exercise and eating a proper diet, are also helpful in delaying or preventing certain forms of cancer. Diabetic patients are advised to ask their physician about getting screened for some cancers earlier and more frequently than individuals without diabetes.

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Review Date: 03-20-2007

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