• The first stage (systole) makes a sound as the two valves between the upper chambers (the atria) and the lower chambers (the ventricles) close. The valve between the left atrium and the left ventricle is called the mitral valve, and the valve between the right atrium and the right ventricle is called the tricuspid valve. The closed valves keep blood from leaking prematurely from the upper chambers to the lower chambers of the heart.