Cervical Rx: HPV Vaccine
Reviewed By:
Joanne Poje Tomasulo, M.D., ACOG
The next time you take your adolescent or
teenaged daughter in for a physical exam, the pediatrician may ask
if you have heard about the new vaccine to help prevent cervical
cancer.
Parents should be prepared to ask questions
about the immunizations and to answer their daughters' questions as
well.
Approved in June 2006, the vaccination is
approved to immunize girls and young women against four strains of
the genital human papillomavirus (HPV), which cause 70 percent of
cervical cancers and 90 percent of genital warts. The cervix is the
lower section of the uterus that leads into the vagina.
HPV is contracted through sexual intercourse or skin-to-skin
contact of infected areas. In most cases, the virus causes no harm.
However, the virus can infect healthy cells in the cervix, causing
them to grow abnormal precancerous lesions. If left untreated,
those lesions can develop into cervical cancer, which kills about
3,800 women a year, according to the American Cancer Society.
The HPV vaccinations are administered as a series of three shots
over a six-month period. They are recommended for 11- and 12-
year-old girls and may be given to girls as young as 9 and to women
up to age 26. The vaccine may be controversial because recipients
are adolescent girls and HPV is a sexually transmitted disease.
However, the vaccine is most effective at preventing HPV if it is
given before a girl is exposed to HPV, which means before she is
sexually active.
After sexual activity begins, there is increased risk of HPV
infection and the vaccine may not work as well if the virus is
already present. According to the Centers for Disease Control and
Prevention, about 6.2 million people are infected each year with
HPV. Most of them are men and women in their late teens and early
20s. Thus far, the HPV vaccine is not approved for boys or
men.
Some parents have balked at the idea of adding yet another
vaccination to the list of childhood immunizations already
administered to children. The vaccine does not contain any live
virus. Side effects of the vaccination include soreness at the
injection site and some reports of fainting. Some states have
introduced or passed legislation to make the vaccine mandatory for
school, although parents can sign a waiver if they do not want
their daughters to have it.
Even with the vaccine, women still need regular Pap screening tests
for cervical cancer. The vaccine protects against the most common
HPV strains, but other strains may also cause cervical cancer. Pap
tests are recommended beginning three years after a girl or woman
becomes sexually active and no later than age 21.
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