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Clot Busting Drugs

Also called: APSAC, Tissue Plasminogen Activator, rt-PA, Thrombolytic Enzymes, Thrombolytic Drugs, Thrombolytic Agents, t-PA

- Summary
- About clot-busting drugs
- Conditions treated
- Conditions of concern
- Potential side effects
- Drug or other interactions
- Symptoms of overdose
- Pregnancy use issues
- Child use issues
- Elderly use issues
- Questions for your doctor

Reviewed By:
Kerry Prewitt, M.D., FACC
Abdou Elhendy, MD, PhD, FACC, FAHA
Robert I. Hamby, M.D., FACC, FACP

Questions for your doctor

Preparing questions in advance can help patients to have more meaningful discussions with their physicians regarding their conditions. Patients may wish to ask their doctor the following questions related to clot-busting drugs:

  1. Are clot-busting drugs used for my type of heart attack or stroke?

  2. How quickly were they administered in my case?

  3. Do I need to give consent before a physician administers clot-busting drugs?

  4. Will I need to continue with anticoagulant medication? For how long? Which one?

  5. What other medications will I need to take? Antiplatelets?

  6. How long will it be before the risk of complications from the clot-busting drugs decreases?

  7. What kind of complications can occur? Is there an increased risk of hemorrhage due to the clot-busting drugs even days or weeks after they are used?

  8. Is it possible I will still need surgery for heart disease?

  9. Are any other procedures, such as balloon angioplasty and stenting, warranted in my case?

  10. Are there any lifestyle changes I can make to help prevent another vascular event?

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Review Date: 03-07-2007
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