Heart disease is the leading killer of both women and men, but when it comes to cholesterol, the sexes were not created equal. The skinny:
Before menopause, naturally high levels of estrogen can help women maintain healthy cholesterol levels and protect them from heart disease. When estrogen starts to decline at menopause (average age, 51) or by removal of the ovaries, HDL levels typically drop, too.
HDLs over 60 mg/dL are considered optimum for both men and women. Men are considered to have low HDL cholesterol at less than 40 mg/dL. Women have low HDL cholesterol at less than 50 mg/dL.
The National Institutes of Health recommend that both men and women begin having their cholesterol tested every five years in their 20s. The exception? Young women who take birth control pills may need earlier and more frequent testing because the hormones in oral contraceptives may affect cholesterol levels and may enhance coagulation (blood clotting). The estrogen in oral contraceptives appears to increase HDLs, triglycerides and total cholesterol levels, yet it decreases LDLs. Progestin in oral contraceptives seems to have the opposite effect. If you take oral contraceptives, discuss cholesterol testing and other risk factors with your physician.
Cholesterol medications appear to work differently in men and women. In several studies of statins, for example, women seemed to reap fewer benefits and suffer more side effects than men.
Every day researchers are learning more about cholesterol, helping to shape better diagnostic testing and treatment. Get the latest updates.
More Cholesterol Resources
Looking for more information? Follow these links to learn more about lowering your cholesterol with exercise, a healthier diet and medication if necessary.