• A family history of cardiovascular disease.

  • Race. According to the American Heart Association, blacks (both male and female) are more likely to have coronary artery disease (CAD) than whites. Proportionately, CAD claims more black and white lives than Hispanic lives. Black women and Native American women are more likely to have a heart attack than white women.

  • Congenital disease heart. These are conditions that are present at birth. Although there is no known cause or preventive measures to protect against congenital heart disease, researchers are pursuing possible genetic causes that may someday lead to better therapies and diagnostic tools.

  • Patient history. Patients who have had cerebral vascular disease (e.g., stroke) are at higher risk of developing CAD.