Corticosteroids are a group of anti-inflammatory drugs similar to hormones produced by the body. They are used to treat a variety of skin conditions, including eczema, urticaria, keloids, pruritus, lichen sclerosus and psoriasis. Corticosteroids are also particularly effective in treating rashes caused by allergies or inflammatory reactions to poison ivy, metals, cloth or other substances.

Corticosteroids can be taken in several forms, with each of the different forms used to treat different conditions. These forms include:

• Topical treatments. Used to treat inflammation of the skin (e.g., eczema, rash).
  
  
• Oral methods (e.g., pills, liquids). Used to quickly treat allergy and asthma episodes (e.g., allergic reaction, asthma attack). They may also be used to treat some skin conditions.  
  
  
• Intravenous (I.V.) methods. Used to quickly treat allergy and asthma episodes, and usually administered by a physician. They may also be used to treat some skin conditions. 

Most corticosteroids are available only with a physician’s prescription. However, some low potency topical creams are available over-the-counter.

Corticosteroids can have a wide range of serious side effects, including a loss of bone density. Some of these side effects may affect the skin. For example, prolonged use of potent corticosteroids may cause thinning of the skin. This is particularly true in some areas of the body (such as the face) and in some populations (such as children and the elderly).  Many medications can interfere with corticosteroids, and these drugs should be used only after talking with a physician.