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Crohn's Disease

- Summary
- About Crohn's disease
- Potential complications
- Types and differences
- Risk factors and causes
- Signs and symptoms
- Diagnosis methods
- Treatment options
- Prevention methods
- Coping with Crohn's Disease
- Ongoing research
- Questions for your doctor

Reviewed By:
David Friedel, M.D., AGA

Ongoing research regarding Crohn's disease

Research continues into additional medical treatments for CD. These include:

  • Interleukin 10 (IL-10). A chemical that suppresses inflammation. The effectiveness of laboratory produced IL-10 in treating CD is being studied.

  • Antibiotics. Currently used to treat infections that may occur in patients with CD. Some research suggests that antibiotics may be useful to treat CD itself.

  • Methotrexate and cyclosporine. Two types of immunosuppressants that appear to work faster than traditional immunosuppressants.

  • Natalizumab. An experimental drug being tested for treatment of CD. It works by keeping white blood cells in the bloodstream, preventing them from reaching and further irritating inflamed areas. However, research has been halted due to potentially serious side effects.

  • Zinc. A mineral that removes free radicals (molecules produced during processes such as fat metabolism, stress, infection) from the blood. Free radicals are believed to contribute to inflammation. Research is under way to determine whether supplements of zinc may reduce inflammation.
In addition, non-traditional complementary treatments for CD are being explored. Acupuncture (thin needles inserted at specific areas to relieve pain) has traditionally been used to treat inflammatory bowel disease in China. It is now increasingly being applied in western countries and appears to benefit patients with mild to moderate CD.

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Review Date: 12-06-2006
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