• Antihypertensives (drugs that slow heart rate or lower blood pressure) such as ACE inhibitors. Although commonly prescribed for diabetics, these can strengthen the effects of diuretics and potentially lead to low blood pressure (hypotension).

  • Psychiatric medications. Some diuretics can cause a build-up of these medications in the blood, increasing the chance of side effects.

  • Licorice. Eating certain types of licorice while taking diuretics may cause excessive potassium loss.