The actual movement of the catheter should be painless, and the risk of complications during this procedure is low. Although rare, these risks include:

The risk of complications of any kind is generally less than 1 percent, but can vary depending on the number of additional procedures (e.g., catheter ablation) that may be performed during the electrophysiology (EP) study. In addition, patients with heart-related conditions such as aortic stenosis, hypertrophic obstructive cardiomyopathy and severe coronary artery disease are not considered candidates for EP testing.