• Fever, which may be low grade, particularly with subacute endocarditis

  • Chills

  • Weight loss

  • Shortness of breath

  • Persistent cough

  • Night sweats

  • Headache

  • Arthritis, or joint pain

  • Back or chest pain

  • Dark red lines of bleeding under the nails (splinter hemorrhages)

  • Tiny, purplish-red pinpoint spots of bleeding under the skin (petechiae)

  • Painless bumpy nodules on the palms of the hands and soles of the feet

  • Tender spots under the skin on the pads of the fingers (Oster’s nodes)