Treatment of fatigue often involves addressing the underlying condition. If a medication or other medical treatment is a contributing factor, the patient's treatment plan may be adjusted where feasible.

Treatment methods for fatigue may include:

• Exercise. Many patients can help combat fatigue with regular exercise, which can:
  
  
• • Enhance their mood
    
  • Increase their energy
    
  • Improve their endurance, strength and stamina
    
  • Increase their appetite
    
  • Facilitate sleep (if completed at least several hours before bedtime)
    
  • Prepare them for the challenges of other conditions and their treatments

Patients are generally advised to begin with short periods of low-intensity exercise, such as leisurely walking, and gradually increase the duration and intensity level of exercise over time (when appropriate). In many cases of individuals experiencing chronic pain or conditions, exercising is difficult. Patients should speak with their healthcare professionals to determine appropriate exercises for their condition.

• Schedule of activity and rest. Patients who experience fatigue should prioritize their daily activities and use a schedule to conserve their energy. A physician or occupational therapist can help devise an activity and rest program that allows the patient to conserve the maximum amount of energy. Patients may reduce fatigue and improve their sleeping habits by:
  
  
• • Lying down only when ready for sleep
    
  • Limiting nap times during the day to allow sleeping at night
    
  • Increasing their activity level during the day
    
  • Eliminating distracting noises during sleep times
    
  • Eliminating foods at bedtime that could interfere with sleep
    

Patients should set realistic activity goals and, as needed, avoid overexerting themselves by using equipment aids (e.g., a ramp instead of stairs or an electric cart at the supermarket). These aids can help patients conserve energy, especially if the activities can cause pain in addition to fatigue.

Patients may also benefit from enlisting the help of others when errands and housework become too difficult. In addition, patients who work may choose to speak with their employer about modified responsibilities and flexible scheduling if need be. Many patients also benefit from maintaining an activity diary, which allows them to identify activities that are particularly taxing.

• Maintain adequate hydration and nutrition. Patients are sometimes advised to drink a minimum of eight glasses of liquids every day to remain sufficiently hydrated. They should also eat a balanced and nutritious diet with enough calories, complex carbohydrates (vegetables, fruits and whole grains), proteins, beneficial fats (e.g., monounsaturated and omega-3) and vitamins to provide sustained energy sources and help the body meet its energy demands.

Patients may choose to speak with a dietician regarding ways to maximize their nutritional intake. Patients may also benefit from taking a multivitamin.

• Reduce and manage stress. Patients experiencing fatigue may benefit from reducing their stress. This can be achieved by learning stress management and relaxation techniques, such as meditation and yoga. Treatments such as biofeedback, hydrotherapy or massage therapy may help.
  
  
• Avoid activities that contribute to their pain. Patients should determine which activities and exercises can be tolerated without adding to their pain. They should choose activities that help lessen their fatigue and improve their well being.

People experiencing fatigue are often advised by their physician to avoid stimulants. Caffeine and other stimulants are not effective in the treatment of fatigue because they may worsen the disorder in the long run by disturbing sleep. Alcohol, nicotine and illegal drugs should also be avoided. In addition, a physician may advise against taking sedatives, which can also worsen the condition.  

Patients are encouraged to monitor the level of their fatigue and contact their physician should its severity increase.