The two main types of Hodgkin’s lymphoma are classical Hodgkin’s lymphoma and nodular lymphocyte predominant Hodgkin’s lymphoma.

• Classical Hodgkin’s lymphoma has four subtypes, all of which have classically appearing Reed-Sternberg cells.
  
• • Nodular sclerosis Hodgkin’s lymphoma. This type mainly occurs in younger people, usually in females. The most common type of Hodgkin’s lymphoma in developed countries, this form tends to start in the lymph nodes of the chest and neck.
    
    
  • Mixed cellularity Hodgkin’s lymphoma. Seen mainly in adults, this is the second most common type of Hodgkin’s lymphoma. Although it can occur in any lymph node, it most often occurs in the upper half of the body.
    
    
  • Lymphocyte-rich Hodgkin’s lymphoma. This type is very similar to mixed cellularity Hodgkin’s lymphoma, except when examined under a microscope, most of its cells are small lymphocytes.  It also occurs most often in the upper half of the body and is rarely found in more than a few lymph nodes.
    
    
  • Lymphocyte-depleted Hodgkin’s lymphoma. The least common type of Hodgkin’s lymphoma, this form is more likely to involve the abdominal lymph nodes, as well as the spleen, liver and bone marrow. It is usually seen in older adults.
    
    
• Nodular lymphocyte predominant Hodgkin’s lymphoma. This type does not usually contain Reed-Sternberg cells. Instead, it contains large cells that resemble popcorn. These “popcorn cells” are somewhat of a cross between the Reed-Sternberg cell and normal lymphocytes. Capable of occurring at any age, this type usually involves lymph nodes in the neck and under the arm.