Intimate allergies are reactions related to sexual activity. Examples include semen allergy and allergies to the latex, lubricant or spermicide found in condoms. Symptoms can be either localized (appearing in one area, such as the genital area) or generalized (appearing throughout the body).

Semen allergy is an uncommon but potentially severe reaction to male ejaculate. The first case of semen allergy was reported in 1958. Both women and men can react to semen, which is made up of sperm and the liquid in which sperm swim. This liquid contains secretions from the prostate gland, Cowper’s glands, seminal vesicles and urethral glands. It is believed that chemicals from these glands are the source of most semen allergies.

Because the chemicals and proteins in semen are foreign substances, the immune system can perceive them as invaders, triggering an allergic reaction. Certain medications (e.g., penicillin) and foods (e.g., walnuts) have also been found to trigger reactions when transmitted through seminal fluid.  An individual may be allergic to one partner’s semen or to the semen of all partners. It is also possible for men to develop an allergy to their own semen.

Some intimate allergies are related to substances associated with intimacy. For example, those with latex allergies may react to condoms or diaphragms made of that material. Some people also have allergies to the spermicides and lubricants used on condoms.

Allergies to semen may be prevented by the careful use of condoms during sexual activity to avoid any exposure to semen. Intimate allergies related to latex allergy may be prevented by the patient and patient’s sexual partner using a different type of condom, like polyurethane. Allergies to spermicide may be prevented through avoiding condoms with spermicide. Lubricant allergies may be prevented by using an alternate lubricant. Patients can consult a physician for recommendations for alternate types of lubricants or condoms.