Why are some people allergic to these substances while others are not?

Scientists think that people inherit a tendency to be allergic, meaning an increased likelihood of being allergic to one or more allergens, although they probably do not have an inherited tendency to be allergic to any specific allergens. Children are much more likely to develop allergies if their parents have allergies, even if only one parent is allergic. Exposure to allergens at certain times when the body's defenses are lowered or weakened, such as after a viral infection or during pregnancy, seems to contribute to the development of allergies.

What is an allergic reaction?

Normally, the immune system functions as the body's defense against invading agents such as bacteria and viruses. In most allergic reactions, however, the immune system is responding to a false alarm. When an allergic person first comes into contact with an allergen, the immune system treats the allergen as an invader and mobilizes to attack. The immune system does this by generating large amounts of a type of antibody (a disease-fighting protein) called immunoglobin E, or IgE. Each IgE antibody is specific for one particular allergenic (allergy-producing) substance. In the case of pollen allergy, the antibody is specific for each type of pollen: one type of antibody may be produced to react against oak pollen and another against ragweed pollen, for example.