Signs and symptoms of liver disease vary according to the type of disease. In the early stages of some types of diseases, patients may experience no symptoms. In the early stages of others, symptoms may be mild and may include:

• Fatigue
• Weakness
• Unexplained weight loss
• Loss of appetite
• Nausea or vomiting
• Fever
• Bruising

In the later stages of liver disease, signs and symptoms may include:

• Jaundice (yellowing of the skin and whites of the eyes)
  
  
• Enlarged liver
  
  
• Ascites (fluid buildup in the abdomen)
  
  
• Encephalopathy (confusion that results from deterioration of brain function)
  
  
• Cholestasis (reduction or stoppage of bile flow)
  
  
• Varices (stretched veins) that can lead to gastrointestinal bleeding
  
  
• Portal hypertension (high blood pressure in the portal vein)
  
  
• Itching
  
  
• Spiderlike blood vessels, red palms or bright red complexion of the skin
  
  
• Anemia (decreased number of red blood cells)
  
  
• Leukopenia (decreased number of white blood cells)
  
  
• Thrombocytopenia (decreased number of platelets)
  
  
• Coagulopathy (tendency to bleed)
  
  
• High glucose (blood sugar) levels
  
  
• Cessation of menstrual cycle and decreased fertility in women
  
  
• Erectile dysfunction (impotence) in men
  
  
• Increased heart rate and amount of blood pumped
  
  
• Hypotension (low blood pressure)
  
  
• Liver failure