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Metformin & PCOS

- Summary
- About metformin
- Conditions of concern
- Potential side effects
- Drug or other interactions
- Pregnancy use issues
- Questions for your doctor

Reviewed By:
Joanne Poje Tomasulo, M.D., ACOG
 Marc Kaufman, M.D., ACOG

Pregnancy use issues with metformin

Metformin is not known to be associated with birth defects or other problems in humans. However, the drug is not often prescribed to women who are pregnant. Women should tell their physician if they are pregnant or considering becoming pregnant before beginning treatment with metformin.

It is not known if metformin passes into breast milk. Women who are breastfeeding should consult with their physician before taking metformin.

Questions for your doctor regarding metformin

Preparing questions in advance can help patients have more meaningful discussions with their physicians regarding their conditions. Patients may wish to ask their doctor the following questions about metformin:

  1. The FDA hasn’t yet approved metformin to treat PCOS – can I still use it?

  2. How will metformin help my condition? 

  3. What risks are associated with the drug?

  4. Will metformin affect my fertility?

  5. How long will I need to stay on metformin? 

  6. How will this drug help my PCOS?

  7. Do I have medical conditions that prevent me from using metformin?

  8. I’m pregnant – how will this affect my ability to use metformin?

  9. I’m breastfeeding – how will this affect my ability to use metformin?

  10. I have diabetes and PCOS – is metformin a good treatment choice for me?

  11. How will I know if I have a problem with metformin?

  12. What are my options if I develop problems with this medication?

  13. How will my condition be monitored?

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Review Date: 12-27-2007

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