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Monosodium Glutamate Sensitivity

Also called: MSG Reaction, Chinese Restaurant Syndrome, MSG Sensitivity

- Summary
- About MSG sensitivity
- Potential causes
- Signs and symptoms
- Diagnosis, treatment and prevention
- Questions for your doctor

Reviewed By:
Marc J. Sicklick, M.D., FAAAAI, FACAAI

Diagnosis, treatment and prevention

There are no established ways to diagnose or treat monosodium glutamate (MSG) sensitivity. If MSG is suspected to be the cause of any symptoms, it is best to avoid MSG in packaged foods and restaurant foods and seek a physician’s care.

Patients should inquire about the ingredients in restaurant foods and avoid ordering and eating foods that contain MSG. Individuals trying to avoid MSG should also read food labels carefully and avoid purchasing or consuming products with MSG listed as an ingredient.

While the U.S. Food and Drug Administration (FDA) requires manufacturers to list MSG on the label of any food to which it is added, there are other glutamate additives that some claim may induce similar symptoms. These additives do not have to be listed on the label as containing MSG because they are chemically distinct. Despite not being scientifically proven, some people report that these additives may cause adverse reactions in people who are sensitive to MSG.

Food additives that contain glutamates include:

  • Hydrolyzed protein
  • Autolyzed yeast
  • Sodium caseinate
  • Calcium caseinate
  • Textured protein
  • Monopotassium glutamate
  • Maltodextrin
  • Modified food starch

MSG is not only used in processed foods but may also be found in dietary supplements, cosmetics, drugs and personal care products. Individuals should consult a physician for advice regarding MSG sensitivity and avoidance strategies.

There have been studies conducted to determine the safety of MSG for pregnant or lactating women which conclude that MSG does not affect women, fetuses or pass through breast milk.

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Review Date: 03-27-2007
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