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Using decongestant nasal sprays over a long period of time or overusing them can result in rebound congestion (rhinitis medicamentosa). This occurs when the nose becomes so conditioned to the medication that it goes through “withdrawal” after being deprived of it. This triggers swelling that causes congestion to increase.

For this reason, nasal decongestants should never be used for more than three to five consecutive days. To prevent rebound congestion:

• Closely adhere to the directions on the packaging and from physicians and pharmacists.
  
  
• Use the medication only as directed.
  
  
• Use the smallest dose possible. Try to limit frequency of use, and do not use the medication at all unless absolutely necessary.
  
  
• Never use for more than three to five days. If there is no improvement after that time, call a physician.

Patients who develop rebound congestion can reverse their body’s “addiction” to the drug by ceasing use of the spray for several weeks. Other forms of medication, such as oral medications or saline nasal sprays, can be used during this time to treat nasal congestion and other symptoms.

Other potential side effects of nasal sprays include:

• Nasal ulcers
• Headache
• Nasal congestion
• Nasal bleeding
• Nose bleeds
• Pain, burning or irritation in the nose
• Runny nose
• Sore throat
• Drowsiness
• Thrush infection in the mouth
• Unpleasant taste
• Mild dryness
• Abdominal pain
• Diarrhea
• Vomiting
• Dizziness