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Since nicotinic acid (niacin) is a vitamin that occurs naturally in food, it does not generally cause problems with other medications. However, the amount of nicotinic acid needed to treat high cholesterol is significantly higher than what is ingested as part of a normal diet. Therefore, patients should consult their physician before taking any other medication, either prescription, over-the-counter or nutritional supplements. Vitamin E supplements, for example may block the effects of nicotinic acid and statins. Of particular concern for patients taking large doses of niacin are:
- Other cholesterol-reducing drugs. Taking more than one cholesterol reducer at a time may worsen side effects. While physicians often prescribe nicotinic acid in combination with other cholesterol-reducing medications, it is important that such combinations only be attempted under the direction of a physician. Individuals taking cholesterol-reducing drugs should not begin taking niacin supplements before consulting with their physicians.
- Antihypertensives. Medications to treat high blood pressure. The effects of these medications may be increased in those also taking high dose niacin pills
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