The signs and symptoms of overdose can be similar to the medication’s side effects, but are usually more severe. Patients exhibiting any of these symptoms should contact their physicians immediately:

The effects of nitrates during pregnancy have not been studied. However, large doses of nitrates in pregnant animals have been found to produce adverse effects on the fetus. Use during pregnancy is not recommended.

It is not known whether nitrates pass to nursing babies through breast milk. Patients should consult their physician about taking nitrates when breastfeeding.

There is no indication that the risk of side effects from nitrates is different in children than in adults. However, the safety of nitrate use in children has not been scientifically established. Parents are encouraged to discuss the potential risks and benefits with a pediatric cardiologist, before their children begin nitrate treatments.

Older adults report a higher frequency and intensity of side effects such as dizziness or lightheadedness. Generally, older patients require lower doses of nitrates.