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The U.S. Food and Drug Administration (FDA) has approved about two dozen types of nonsteroidal anti–inflammatory drugs (NSAIDs). Each type of NSAID affects the body differently, with individuals responding better to some types than others.
Physicians often switch among different NSAIDs for a patient to find the drug that is the most effective with the fewest side effects. The choice of one NSAID over another should be made after considering an individual’s risk factors for these potential side effects.
Among the NSAIDs are subgroups of medications, such as:
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Salicylates. Aspirin and related drugs, such as salsalate.
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COX-2 inhibitors. Drugs designed to relieve pain and inflammation without upsetting the stomach. Celecoxib remains the only COX-2 inhibitor sold in the United States after rofecoxib and valdecoxib were withdrawn because of side effects.
NSAIDs approved for sale in the United States include:
| Generic Name |
Brand Name(s) |
| aspirin |
Adprin, Alka–Seltzer, Ascriptin, Aspergum, Bayer, Bufferin, Darvon, Easprin, Ecotrin, Excedrin, Gelpirin, Genacote, Goody’s, Halfprin, Magnaprin, Norwich, PC-CAP, Percodan, Roxiprin, St. Joseph, Supac, Sureprin, Talwin, Vanquish, ZORprin
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| celecoxib |
Celebrex |
| choline salicylate |
Arthropan |
| choline magnesium salicylate |
Trilisate |
| diclofenac |
Cataflam, Solaraze, Voltaren |
| diflunisal |
Dolobid |
| etodolac |
Lodine |
| fenoprofen |
Nalfon |
| flurbiprofen |
Ansaid |
| ibuprofen |
Advil, Bayer Select Ibuprofen, Cramp End, Dolgesic, Excedrin, Genpril, Haltran, Ibifon, Ibren, IBU, Ibuprin, Ibuprohm, Ibu-Tab, Medipren, Menadol, Midol, Motrin, Nuprin, Pamprin, Q-Profen, Rufen, Trendar |
| indomethacin |
Indocin, Indocin SR |
| ketorolac |
Toradol |
| ketoprofen |
Actron, Orudis, Oruvail |
| magnesium salicylate |
Doan’s, Keygesic, Mobidin, Momentum, Novasal |
| meclofenamate |
Meclomen |
| mefanamic acid |
Ponstel |
| meloxicam |
Mobic |
| nabumetone |
Relafen |
| naproxen |
Aleve, Anaprox, Naprelan, Naprosyn |
| oxaprozin |
Daypro |
| phenylbutazone |
Cotylbutazone |
| piroxicam |
Feldene |
| salsalate |
Argesic, Disalcid, Mono-Gesic, Salflex, Salsitab |
| sulindac |
Clinoril |
| tolmetin |
tolectin |
There are also many combination products that mix an NSAID with other ingredients, such as an anti-anxiety agent, an anticoagulant, a barbiturate, caffeine, a decongestant, an opioid or a sleep aid.
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