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NSAIDs

Also called: Antiprostaglandins, Nonsteroidal Anti-Inflammatory Drugs

- Summary
- About NSAIDs
- Types and differences
- Conditions treated
- Conditions of concern
- Potential side effects
- Drug or other interactions
- Symptoms of overdose
- Pregnancy use issues
- Child use issues
- Elderly use issues
- Questions for your doctor

Reviewed By:
Vikas Garg, M.D., MSA

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Symptoms of NSAIDs overdose

Symptoms of overdose can be similar to the side effects of nonsteroidal anti-inflammatory drugs (NSAIDs), but are usually more severe. Patients exhibiting any of these symptoms should contact their physician immediately:

Bluish lips, skin or fingernails
Severe and lingering headache
Nausea or vomiting
Difficulty breathing
Fast or pounding heartbeat
Confusion, agitation or incoherence
Blurred vision
Skin rash
Ringing in the ears
Abdominal pain or diarrhea
Convulsions or seizures
Hemorrhage (heavy bleeding) from stomach or intestine

In rare cases, the patient may also go into a coma (prolonged unconsciousness).

Pregnancy use issues with NSAIDs

Pregnant women should avoid taking nonsteroidal anti-inflammatory drugs (NSAIDs) unless otherwise directed by a physician who is familiar with their condition. Though human studies evaluating birth defects caused by NSAIDs are unavailable, these drugs can potentially cause heart or blood flow problems in fetuses and newborns. Animal studies demonstrate a link between NSAID use and complications with pregnancy and delivery.

Many NSAIDs pass into the breast milk of breastfeeding mothers. Furthermore, several are believed to cause unwanted effects in nursing children. Nursing mothers should avoid taking NSAIDs and are encouraged to discuss possible drug alternatives with their physicians.

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Review Date: 02-16-2007

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