The link between insulin resistance and polycystic ovarian syndrome (PCOS) is leading researchers to examine the effects of medications used in diabetes treatment on patients with this hormonal imbalance.

There is promising evidence that shows the use of metformin (a type of insulin sensitizer) to be highly successful in regulating the menstrual cycle and lowering body mass index (BMI). It may also help overall cholesterol levels and increase ovulation and fertility, although some studies show that traditional fertility medications such as clomiphene are more effective in achieving pregnancy.

Research is also continuing in other disease areas for which women with PCOS have an increased risk, such as cardiovascular disease and metabolic syndrome. Cardiac risk factors such as increased LDL cholesterol and cardiac calcium levels are being studied in PCOS patients and how much those increased levels contribute to heart disease.

For the most part, research is still being conducted to better understand the underlying causes of PCOS. In addition, treatment using natural progesterone and laser therapy to improve ovulation are being studied in women. Ongoing studies are starting to confirm the belief that women with this hormonal imbalance who obtain proper treatment can live healthier lives, and may even have healthy pregnancies.