Though all women are strongly encouraged to seek prenatal medical care as soon as they become pregnant, it is especially important for women with heart-related conditions. These women are urged to consult a physician and other qualified healthcare professionals prior to becoming pregnant to discuss possible complications. Heart-related conditions that may be of concern to mothers-to-be include:
Heart murmur
Rheumatic fever
High blood pressure (hypertension)
Diabetes
Congenital heart disease
Deep vein thrombosis
Heart failure
Coronary artery disease
Marfan syndrome
Pulmonary hypertension
A disorder that involves abnormal heart rhythms or arrhythmias(e.g.,Long QT syndrome)
A disease of one or more valves of the heart (valvular disease), including an implanted valve
Even a normal pregnancy places extraordinary demands on the heart. For example, cardiac output, or the amount of blood pumped by the heart, may increase 30 to 50 percent during the latter stages of a pregnancy. During labor and delivery, it may increase by 80 percent. Similarly, the maternal heart rate increases by 15 to 20 beats per minute. As a result of these changes, existing heart disease may be aggravated or new heart conditions may develop.
There is also the possibility that the fetus is at increased risk for heart complications. For example, some heart defects appear to run in families. A baby born to a parent (male or female) who has a heart condition has an increased chance of having congenital heart disease. It has also been shown that a family history of early heart disease on the mother’s side increases the risk for delivering a low birthweight baby.
Women with heart disease are strongly encouraged to work closely with their physicians before and during their pregnancy. Before pregnancy, all heart patients should obtain a full check-up, which includes a medical history, physical examination, echocardiogram and electrocardiogram. These tests will measure the function of the heart and establish and important baseline for the physician to use during the pregnancy. During the pregnancy, the expectant mother should be monitored by her physicians and closely follow all instructions. Medications may be altered, lifestyle changes may be recommended and fetal monitoring (e.g., ultrasound) may be increased. Issues to consider for the patient and child by the physicians include:
Abnormal heart rhythms (arrhythmias)
Problem with the pumping chambers of the heart (ventricles)
The need for maintenance with medication, including antibiotics and anticoagulants
Some heart-related conditions carry greater dangers for the mother and/or the child. Expectant mothers are encouraged to work with their physicians to determine which approach (e.g., medication or bed rest) is the most appropriate. Studies show that good prenatal care, which includes close physician participation throughout the pregnancy, increases the chances of a healthy mother and baby.
About pregnant heart patients
Pregnancy causes wide-ranging and profound changes in the expectant mother’s cardiovascular and circulatory system. For example, during the later stages of pregnancy, cardiac output increases between 30 and 50 percent. During labor, the mother’s cardiac output increases up to 80 percent. This increase is connected to the greater volume of blood circulating in the mother’s body and her increased heart rate, which is typically increased by 15 to 20 beats per minute. Despite the increased blood volume and cardiac output, however, blood pressure typically falls during a healthy pregnancy.
In women with existing heart disease, pregnancy carries extra risks. Their heart disease may become worse, or they may have to stop taking medications to control their disease. For example, statin medications, which are used to lower cholesterol, and ACE inhibitors, which are used to treat heart failure and hypertension, are not recommended during pregnancy. In years past, rheumatic heart disease was the most common cardiac complication among pregnant women. However, because of improved medical techniques that enable more infants to survive to childbearing age, congenital heart disease is now the leading cardiac complication among pregnant women. Also, because more women are postponing childbirth until they are in their 30s or 40s, it is more common to see expectant mothers with high blood pressure, diabetes and elevated cholesterol levels.
Any cardiac condition is a cause for concern, and heart patients who wish to become pregnant, or who are pregnant, are strongly encouraged to consult with their physician. The standard check-up for pregnant heart patients includes a medical history, physical examination, echocardiogram and electrocardiogram. These tests provide the physician with a complete picture of how the expectant mother’s heart and circulatory system are responding to the pregnancy.
If there is concern, bed-rest may be ordered. Studies have shown that the stress placed upon the heart depends in part on the expectant mother’s posture. Lying down can decrease the cardiac output by up to 30 percent. Conversely, however, some heart disease patients are at increased risk for blood clots during their pregnancy. Blood clots are a leading cause of maternal death among all women, but women who have certain inherited conditions, or who have artificial heart valves, are at especially elevated risk. In this case, the physician may recommend standing or sitting in certain positions and staying active to encourage adequate blood flow through the legs, where blood clots normally form.
During delivery, many physicians will allow the expectant mother to go into labor naturally and attempt a vaginal delivery. Studies have shown that vaginal deliveries pose less risk to heart patients than Caesarean deliveries. If, however, the mother is at an elevated risk level, then the physician may recommend inducing labor under controlled circumstances. Overall, a pregnant woman’s risk level from heart disease depends on the nature of the disease. Maternal cardiac conditions that carry the lowest overall risk to the mother and fetus include:
Patent ductus arteriosus
Certain lesions in the pulmonic valve or tricuspid valve of the heart
Defects in the septum (the muscular wall between the left and right chambers of the heart)
Mitral valve regurgitation and mitral valve prolapse
Cardiac conditions that carry moderate risk to the mother and fetus include:
Narrowing of the aortic valve (aortic stenosis), which may require surgical repair before pregnancy is recommended
Narrowing of the mitral valve (mitral stenosis)
History of heart attack
Marfan syndrome (with a normal aorta)
Tetralogy of Fallot (a type of heart defect)
Coronary artery disease, which is relatively rare among childbearing women but may result in heart attack
Various arrhythmias, which may range from harmless to very dangerous
High-risk conditions include:
Eisenmenger syndrome (50 percent of these women do not survive pregnancy)
Severe forms of cardiomyopathy, especially affecting the left ventricle
Peripartum cardiomyopathy (a gestational heart-related condition)
Pulmonary hypertension (high blood pressure in the vessels of the lungs)
Artificial heart valves that require anticoagulation
Heart failure
Conditions impacting the baby
Various studies have sought to discover the link between cardiovascular disease and any number of birth issues, from birth weight (the lower the birth weight, the higher the chance for heart disease later in life, according to some studies) to breast-feeding (breast-fed babies have a lower risk of heart disease and of impaired insulin function). While the correlations are not always clear, these studies do prove that good prenatal care, which includes close physician participation throughout the pregnancy, increases the chance of having a healthy baby.
Conditions that affect the cardiovascular system and the developing fetus, as well as the pregnant mother, include:
Hypertension (high blood pressure). High blood pressure can be dangerous for both mother and fetus.
Rubella (German measles). A pregnant woman who is infected with rubella runs up to a 50 percent chance of bearing a baby with birth defects including heart-related congenital defects. Before conceiving, women should speak with their physicians about their medical history, including childhood diseases and immunizations.
Congenital heart disease. Biological mothers or fathers who had some form of congenital heart disease have an increased risk of having a baby with a heart defect.
Preeclampsia (toxemia). A potentially dangerous condition occurring in the second half of pregnancy in which hypertension is accompanied by proteinuria, or an excess of protein in the urine and/or swelling (edema). This is viewed as a potential precursor for eclampsia. The development of preeclampsia during a woman’s first pregnancy has been linked to a high risk of heart disease later in life.
Eclampsia. Convulsions, seizures and coma occurring anytime between the 20th week of pregnancy and the first week postpartum (after birth). About one in 200 pregnant patients with hypertension develop this condition. If untreated, it can be fatal.
Arteriovenous malformation (AVM). This is a relatively rare condition in which blood vessels within an organ or body area lack a network of capillaries resulting in arterial blood traveling directly to a vein. This places extra pressure on the vein, and over time, it may weaken and burst, or hemorrhage. Bleeding is usually present. Pain may or may not be present.
Arrhythmias. Pregnancy increases the likelihood of abnormal heart rhythms.
Diabetes. Blood sugar irregularities as well as the vascular complications of diabetes can affect a pregnancy, as well as increase the risk of heart problems in the fetus.
Smoking. Maternal smoking increases the risk of delivering a low birthweight baby. Studies have shown that exposure to second-hand smoke also may increase the risk of having a baby of lower birthweight.
Age. The mother’s age has an effect on the pregnancy and on the developing fetus. Mothers in their 30s and 40s are monitored more closely than others.
Drugs such as warfarin and lithium.
Lupus (a disorder affecting the immune system) may be associated with bradycardia of the newborn.
Some conditions may prevent a healthy delivery. Severe forms of cardiomyopathy and pulmonary hypertension, as well as conditions that involve a right-to-left shunt (e.g., Tetralogy of Fallot), all affect the flow and oxygenation of blood. These heart conditions can significantly affect fetal growth and development. Women with any of these conditions should learn about the associated risks of their condition(s) before becoming pregnant.
High-risk pregnancies
For all pregnant women, especially those whose pregnancies are considered high-risk, healthy habits and precautions are encouraged. These include:
Avoiding smoking and, as much as possible, secondhand smoke.
Avoiding alcoholand illegal drugs.
Taking a prenatal multivitamin before conception and throughout the pregnancy. Most prenatal vitamins include folic acid (folate), a B-vitamin known to help prevent certain birth defects.
Only taking medication (both prescription and over-the-counter) with a physician’s approval.
Eating a nutritious diet.
Women are also encouraged to speak with a cardiologist about which of the four New York Heart Association (NYHA) classifications would best characterize their pregnancy. Women in Class I and Class II are less likely to experience serious complications than women in Class III or Class IV.
Questions for your doctor
Preparing questions in advance can help patients to have more meaningful discussions with their physicians regarding their conditions. Patients may wish to ask their doctor the following questions related to pregnant heart patients:
How can I tell if I have a heart condition that could affect my pregnancy?
What diagnostic tests can evaluate my heart condition?
Could my current heart problem interfere with my pregnancy in any way?
What is the best way to monitor my heart condition throughout my pregnancy?
Will I need to be followed by any specialists during my pregnancy?
Are there any lifestyle changes I can make to increase the chances that my heart problem will not interfere with my pregnancy? Do I need to quit smoking?
Could I develop a heart problem as a result of my pregnancy? If so, how will it be detected?
If my pregnancy does cause me to develop a heart condition, will this condition go away after I give birth? How soon?
Am I at higher risk for heart problems based on my family or medical history?
Is there any way to tell if my heart problem is adversely affecting my unborn child?
Will my heart condition affect the delivery of my child in any way? Do you recommend a vaginal birth or a Caesarian section?
Are there any activities I should avoid during my pregnancy?
What are the chances my child will inherit the same heart condition?