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Prokinetics

Also called: Prokinetic Drugs, Prokinetic Medications

- Summary
- About prokinetics
- Conditions of concern
- Potential side effects
- Drug or other interactions
- Symptoms of overdose
- Pregnancy use issues
- Child use issues
- Elderly use issues
- Questions for your doctor

Reviewed By:
Vikram Tarugu, M.D., AGA, ACG

Potential side effects of prokinetics

Prokinetics have been linked to several significant side effects, some of which are potentially fatal. For example, cisapride has been associated with fatal heart arrhythmias (abnormalities in heartbeat rhythm). For this reason, this drug is not prescribed in the United States.

The prokinetic metoclopramide is associated with agitation, depression and severe muscle twitching (tardive dyskinesia). Both men and women may experience painful swelling of the breasts when taking this drug.

Other side effects associated with prokinetics include:

  • Jitteriness
  • Insomnia
  • Sedation
  • Anxiety
  • Diarrhea
  • Dizziness

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Review Date: 02-20-2007

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