Radionuclide imaging is a technique that uses the introduction of tiny amounts of radioactive materials into a patient's body in order to obtain images. The technique allows physicians to obtain very detailed images of different organs in the body, including the heart. Radionuclide imaging also provides information about tissues, blood flow and chemical changes in the body.

Common tests include positron emission tomography (PET) scans and single photon emission computed tomography (SPECT) scans. These scans are used to evaluate a variety of diseases, including cancer and coronary heart disease.

The tests are typically conducted on an outpatient basis with little or no preparation. The exposure to radiation in these tests is fairly low, and most patients can participate in radionuclide imaging without any significant adverse risks. Pregnant or breastfeeding women may be unable to undergo radionuclide imaging.