There are medical research projects investigating the potential of developing a ragweed vaccine to treat ragweed allergy. Researchers at Johns Hopkins School of Medicine are working on a vaccine that contains only specific parts of ragweed allergens. This vaccine is administered one month before ragweed season with two to four injections over a two to three week period. Clinical trials of the vaccine are showing positive signs of treating ragweed allergy.

According to the Journal of Allergy and Clinical Immunology, a new form of immunotherapy is being tested for ragweed allergy. It consists of administering six injections of ragweed allergen over a six-week period. These immune shots are proving effective at treating the symptoms of ragweed allergy while eliminating the need for other allergy medications such as antihistamines and decongestants.