The typical sign of a restrictive cardiomyopathy is heart failure. The primary symptoms of heart failure are:

These symptoms tend to occur during physical activity. This is because the heart with restrictive cardiomyopathy has difficulty delivering oxygen-rich blood during exertion and the pressure within the heart chambers tend to rise. At rest, the heart is still able to pump oxygenated blood. Symptoms may include:

• Nausea or upset stomach
• Loss of appetite
• Symptoms of the underlying disease process such as amyloid and iron deposits in other organs