Treatment for this condition is very challenging. The goal of therapy is to help treat heart failure as well as the underlying disease process, such as chelation of iron excess. Drugs typically used to fulfill this objective include diuretics (which help to flush excess fluids from the body and are used to control high venous blood pressure). Other medications may include:

• Calcium channel blockers. To improve diastolic function.
• Beta blockers. To help control heart rate.
• ACE inhibitors. To improve diastolic function

In some cases, a pacemaker or implantable cardioverter defibrillator may be needed to control arrhythmias. In very severe cases, heart transplantation may be recommended. Since there is no definitive cause for a restrictive cardiomyopathy, there are no known prevention strategies.