Pregnancy use issues with retinoids

Retinoids have been proven to cause severe birth defects when taken by pregnant women or by the mother or father at the time of conception. The drugs have also been linked to miscarriage, premature delivery and infant death. Patients who are pregnant, suspect they are pregnant or plan to become pregnant should not take retinoids. Women who are breastfeeding should also avoid the drug.

Women using retinoids should use two forms of birth control for one month before taking the medications and from one month to three years after treatment to avoid pregnancy. The “mini” birth control pill that contains no estrogen is not considered effective while on this type of medication.

Women using retinoids do not need to use two forms of birth control if they have had a hysterectomy (surgery to remove the womb), have finished menopause (permanent cessation of the menstrual cycle) or practice sexual abstinence.

Child use issues with retinoids

Studies of retinoids have been completed only with adults. No specific information is available for the use of retinoids in children.

Elderly use issues with retinoids

Studies of retinoids have included adults over age 60. Results have shown no difference in the side effects in older patients versus younger adults. However, older adults may be more sensitive to the side effects.