There are numerous types of seizure medications, each of which may be used to treat different seizure conditions.

People with epilepsy may initially be prescribed a first-line medication. These are medications that are the first choice of physicians to treat seizures. In some cases, people may be required to take other medications in addition to these first-line drugs. These additional medications are called add-ons or second-line therapy. Other medications may also be used on a temporary basis. Some medications are available in extended release (XR) formulations, which help to maintain a steady level of the medication in a patient’s body.

Some of the most common seizure medications and their brand names include:

First-line treatments

Add-on treatments

Other medications

Generic substitution of seizure medications can be problematic and may result in breakthrough seizures. Patients should not make a generic substitution without first consulting their physician.