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Theophylline

- Summary
- About theophylline
- Types and differences
- Conditions treated
- Conditions of concern
- Side effects and symptoms
- Drug or other interactions
- Pregnancy use issues
- Child use issues
- Elderly use issues
- Questions for your doctor

Reviewed By:
Marc J. Sicklick, M.D., FAAAAI, FACAAI

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Pregnancy use issues with theophylline

The U.S. Food and Drug Administration has listed theophylline as being category C, which means it is unknown whether or not theophylline is harmful to unborn babies. Those who are pregnant or are considering becoming pregnant should inform their physician. The ability of pregnant women to clear theophylline from the body also decreases in latter months, so a dosage adjustment may be recommended.

Theophylline is passed through breast milk and should not be taken by breastfeeding mothers because of potential risks for nursing infants.

Child use issues with theophylline

Theophylline tends to clear the body more quickly in children between the ages of 1 and 16 than in adults. Therefore, a physician may suggest a dosage adjustment to compensate for this factor.

Theophylline combined with the drug phenytoin (an anticonvulsant) slows the rate at which the drug is removed from the body, which can be an issue for some children.

Elderly use issues with theophylline

Those who are over age 60 are more likely to experience side effects as a result of taking theophylline. The medication also tends to clear the bodies of older adults at a slower rate. As a result, older adults should consult their physician about whether or not they might benefit from taking a lower dose of the drug.

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Review Date: 08-27-2007

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