• Age and gender. Women between the ages of 30 and 50 are more likely to develop neurogenic TOS. Men are more likely to develop venous TOS.

  • Posture. People with poor, slouching postures are more likely to develop TOS.

  • Weight. Overweight and obese people are more likely to develop TOS, although this may be related to posture.

  • Stress and depression. Psychological factors can cause chronic muscle spasms, which may play a role in developing TOS. In addition, stress and depression may be related to weight and posture.